How to Watch Best Medicine Season 2 on DIRECTV: FOX Channel, Time and Streaming
Best Medicine Season 2 airs Tuesdays at 8 p.m. ET/PT on FOX, so DIRECTV customers watch it on their local FOX station. Josh Charles stars as Dr. Martin Best, a blunt, brilliant surgeon who becomes the general practitioner in a small fishing village, with Abigail Spencer as Louisa Gavin and Annie Potts as Aunt Sarah.
Season 2 premiered on September 22, 2026. The next new episode, "Hare Today, Gone Tomorrow" (Season 2, Episode 5), airs Tuesday, October 20, at 8 p.m. ET, with guest star Jack Cutmore-Scott. Here's how to watch Best Medicine on DIRECTV and what to expect during the World Series, as of October 19, 2026.
Best Medicine Season 2 at a glance
| Detail | Info |
|---|---|
| Network | FOX |
| Day and time | Tuesdays, 8-9 p.m. ET/PT (7 p.m. CT) |
| Season 2 premiere | Tuesday, September 22, 2026 |
| Next new episode | "Hare Today, Gone Tomorrow" (S2, E5), Tuesday, October 20 |
| DIRECTV channel | Your local FOX station (number varies by market) |
| Streaming | Live on FOX One with your DIRECTV sign-in |
| Followed by | Doc at 9 p.m. ET |
How to watch Best Medicine on DIRECTV
FOX doesn't have one national channel number on DIRECTV. You get it through your local FOX affiliate, and the number depends on your market. Press Guide and find your FOX station, or search "Best Medicine." A series recording on your Genie DVR or the DIRECTV app's Cloud DVR will catch every new episode. Our guide to what channel FOX is in your area lists stations by market.
FOX One streams FOX live, and DIRECTV says it's included with qualifying plans when you sign in with your DIRECTV account. See is FOX One free with DIRECTV?
Is Best Medicine on during the World Series?
Not on October 27. FOX airs World Series Game 4 at 8 p.m. ET that Tuesday, in Best Medicine's usual slot, so plan on a week off before the next new episode.
What happens in "Hare Today, Gone Tomorrow"
According to FOX, when the wife of a traveling magician duo dies at the Salty Breeze, Martin has to help her husband, who can't grasp that she's gone. Eden finds a letter Martin wrote to Louisa and thinks it was meant for her, and Martin gets a new male medical monitor, played by Jack Cutmore-Scott, who has an instant connection with Louisa.
Best Medicine cast
| Actor | Role |
|---|---|
| Josh Charles | Dr. Martin Best |
| Abigail Spencer | Louisa Gavin |
| Annie Potts | Aunt Sarah |
| Josh Segarra | Sheriff Mark Mylow |
| Cree | Elaine Denton |
| Eliza Coupe | Dr. Eden Montgomery |
| Stephen Spinella | Greg Garrison |
| Jason Veasey | George Brady |
Best Medicine is FOX's American version of the British series Doc Martin.
Frequently asked questions
What channel is Best Medicine on DIRECTV?
Best Medicine airs on FOX, so tune to your local FOX station. FOX doesn't have one national DIRECTV channel number, so the number depends on your market.
What time is Best Medicine on?
New episodes air Tuesdays at 8 p.m. ET/PT (7 p.m. CT) on FOX. The next one, "Hare Today, Gone Tomorrow," airs October 20, 2026.
Is Best Medicine new on October 27?
No. FOX airs World Series Game 4 at 8 p.m. ET on Tuesday, October 27, in Best Medicine's time slot.
Is Best Medicine based on Doc Martin?
Yes. Best Medicine is FOX's American adaptation of the British series Doc Martin, starring Josh Charles.
Can I stream Best Medicine with DIRECTV?
Yes. FOX One streams FOX live, and DIRECTV includes it with qualifying plans when you sign in with your DIRECTV account.
Need help finding FOX on DIRECTV? Call 1-855-690-9884.